Figure 2
From: Application of magnetic techniques in the field of drug discovery and biomedicine
Magnetocapture protein interaction assays. Ni-NTA magnetic agarose beads precharged with nickel captures 6xHis-tagged proteins, which can be used for studying protein-protein (i) and DNA-protein interactions (ii), and immunoassay procedures using antibodies specific for antigens present on the captured 6xHis-tagged biomolecule or antigens present on interaction partners bound to the captured 6xHis-tagged biomolecule (iii). Reprinted, with permission, from materials provided by Qiagen, GmbH, Germany.